Estimation of Age-Appropriate Immunisation Coverage in Assam using Survival Analysis

M. Barman
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Abstract

The widely used measure of immunisation coverage, viz., up-to-date immunisation, is a biased estimator of fraction of vaccinated population. It completely ignores the timeliness in receipt of vaccination, which is important for child health and survival. In this paper, the researcher attempts to study the age-appropriate vaccination pattern of two districts, viz., Dibrugarh and Sibsagar of Assam. Multi-stage cluster sampling method was used to select random sample of children to collect information on immunisation in the study area. The techniques of survival analysis were used to estimate the age-appropriate immunisation with respect to different vaccine doses. The up-to-date immunisation coverage was also calculated for comparison purpose. The results revealed that the timeliness in receipt of different doses of vaccination was very less despite a satisfactory level of up-to-date immunisation coverage. Particularly, by age of 14 weeks (the recommended age for the receipt of third dose of DPT and OPV vaccine), only about 5% children were vaccinated with the third dose of DPT and OPV vaccine; while the up-to-date coverage of the two doses were about 86 and 82%, respectively, in the study area. A similar type of result could be observed in other doses also. Thus, it can be concluded that though the child immunisation coverage in Assam has been increasing, there is still a lot of concern over the timeliness of vaccination coverage, which will be able to provide highest protection against vaccine-preventable disease.
用生存分析估计阿萨姆邦适龄免疫接种覆盖率
广泛使用的免疫覆盖措施,即最新免疫接种,是对接种疫苗人口比例的有偏差估计。它完全忽视了接种疫苗的及时性,这对儿童的健康和生存至关重要。在本文中,研究人员试图研究两个地区,即阿萨姆邦的Dibrugarh和Sibsagar的适龄疫苗接种模式。采用多阶段整群抽样方法,随机抽取研究区儿童进行免疫接种信息收集。生存分析技术用于估计不同疫苗剂量下的适龄免疫接种。为了进行比较,还计算了最新的免疫接种覆盖率。结果显示,尽管最新免疫覆盖率达到令人满意的水平,但接受不同剂量疫苗接种的及时性却非常低。特别是,到14周(建议接种第三剂百白破和口服脊髓灰质炎疫苗的年龄)时,只有约5%的儿童接种了第三剂百白破和口服脊髓灰质炎疫苗;而在研究地区,这两种剂量的最新覆盖率分别约为86%和82%。在其他剂量中也可以观察到类似的结果。因此,可以得出的结论是,尽管阿萨姆邦的儿童免疫覆盖率一直在增加,但对疫苗接种覆盖率的及时性仍然存在很多担忧,这将能够为预防疫苗可预防的疾病提供最高保护。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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