THE PROCESS OF APOPTOSIS IN PATIENTS WITH PATHOLOGY OF THE CERVIX UTERI AND ENDOMETRIAL HYPERPLASIA

D. Najmutdinova, D. Yuldasheva, D. Kayumova, D. Sadikova
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Abstract

Patients with simple endometrial hyperplasia, not accompanied by cervical pathology, as well as at the combination of endometrial hyperplasia and cervical pathology, the level indicators of apoptosis increase which are quite much stated in the latter case. Therefore, in the examination of patients with cervical pathology and/or in the combination with endometrial hyperplasia it is necessary to determine the induction of apoptosis markers - the concentration of p53 and Bcl-2 in blood serum. The definition of these indicators can be used to predict the outcomes of hyperplastic states. Timely diagnosis and adequate monitoring of patients will prevent the development of cervical cancer and hyperplastic processes of endometria.
宫颈病理及子宫内膜增生患者细胞凋亡的过程
单纯性子宫内膜增生,未伴有宫颈病理,以及子宫内膜增生与宫颈病理合并时,细胞凋亡水平指标增加,后者较多。因此,在检查宫颈病理和/或合并子宫内膜增生的患者时,有必要测定诱导凋亡的标志物——血清中p53和Bcl-2的浓度。这些指标的定义可用于预测增生状态的结局。及时诊断和充分监测患者将防止宫颈癌的发展和子宫内膜增生过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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