The Effectiveness of Complex Treatment of Ulcerative Colitis in Integrative Medicine

A. Guli̇yeva, G. Guli̇yeva
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Abstract

The aim of the study was to develop a new complex treatment of ulcerative colitis using integrative medicine methods. The study was conducted on 16 patients with ulcerative colitis with total (8 patients) and left-sided lesions (8 patients). The progress of the disease was traced on the basis of complaints, levels of fecal calprotectin and lactoferrin, ESR and endoscopic picture of the colon mucosa. Depending on the severity and individual characteristics of the progress of the disease, the treatment lasted 2-8 months. The treatment was carried out against the background of taking mesalazine in two stages. At the first stage (1-3 weeks), treatment was carried out to eliminate the causes of the leaky gut syndrome (use of antiparasitic, antibacterial, antiprotozoal drugs) and restore the microbiota (use of eubiotics and short-chain fatty acids). The aim of the second stage of treatment (4-6 weeks) was immunomodulation and regeneration of the intestinal mucosa (the use of bioregulatory, isopathic, orthomolecular drugs and interleukin preparations). Patients received drugs orally, in the form of intravenous infusions and local injections into the metameric zones and acupuncture points of the large intestine. Also, in parallel, neural therapy was carried out with procaine at the points of the large intestine. The results obtained showed a significant decrease in calprotectin, lactoferrin and an improvement in the endoscopic picture of the large intestine. Colonoscopy showed complete recovery in group I in 2, and in group II in 3 patients, in other cases was noted 70% recovery of the mucous membrane. Thus, the use of a complex of integrative medicine methods with the use of safe bioregulatory drugs makes it possible to obtain high efficiency in the treatment of ulcerative colitis.
中西医结合综合治疗溃疡性结肠炎的疗效观察
该研究的目的是利用综合医学方法开发一种新的溃疡性结肠炎综合治疗方法。研究对象为16例溃疡性结肠炎患者,共8例,左侧病变8例。疾病的进展是根据主诉、粪便钙保护蛋白和乳铁蛋白水平、ESR和结肠粘膜内窥镜图像来追踪的。根据病情的严重程度和个体特点,治疗持续2-8个月。治疗以服用美沙拉嗪为背景,分两个阶段进行。在第一阶段(1-3周),进行治疗以消除漏肠综合征的原因(使用抗寄生虫、抗菌、抗原虫药物)和恢复微生物群(使用益生菌和短链脂肪酸)。第二阶段治疗(4-6周)的目的是免疫调节和肠粘膜的再生(使用生物调节,等病,正分子药物和白细胞介素制剂)。患者口服药物,静脉滴注,局部注射到大肠的代谢区和穴位。同时,在大肠点用普鲁卡因进行神经治疗。结果显示钙保护蛋白、乳铁蛋白显著降低,大肠内窥镜图像改善。结肠镜检查显示,I组2例患者完全恢复,II组3例患者完全恢复,其他病例粘膜恢复70%。因此,综合使用安全的生物调节药物的综合医学方法,可以获得治疗溃疡性结肠炎的高效率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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