THE RELATIONSHIP BETWEEN THROMBOSIS AND COVID-19 VACCINES - LITERATURE REVIEW

Abstract

Over the last couple of months, a few cases of thromboembolic events related to COVID-19 vaccines have been described. Those events cause clinicians and institutions to contraindicate the ChAdOx1 vaccine in a subgroup of patients. However, some of these recommendations are not scientifically proven, and delayed vaccination can be more dangerous than the theoretical risk input to these vaccines. Also, the mechanism of thrombosis related to vaccines is quite different from the mechanism usually seen in the outpatient setting of non-hematologists. Additionally, those thrombosis’s clinical picture resembles the Heparin-Induced Thrombocytopenia, and because some patients have clinical and laboratory similarities, this condition was named Vaccine-Induced Thrombotic Thrombocytopenia. This review aims to explain to the medical community, especially those non-hematologists, how to diagnose, manage, and treat this