Histological study on bone response to resin-hydroxyapatite.

O Saitoh, Y Takamori, F Takashima, T Maruyama
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Abstract

Resin-Hydroxyapatite has been developed to take the advantages of bioactivity of hydroxyapatite (HAP) and plasticity of resin (Bis-GMA). It was composed of 75% HAP, 15% Bis-GMA and 10% quartz reinforced filler. Tested pellets of Resin-HAP as well as its constituents were implanted into subcutaneous connective tissue of femurs of adult dogs. Histological observation at 12 weeks postoperatively showed that each pellet was surrounded by the fibrous connective tissue almost free of the inflammatory cells. The thickness of the fibrous layer around HAP was relatively thin, while those around Bis-GMA and Resin-HAP showed some variance. Taking our previous data into consideration, it was suggested that Resin-HAP had bio-compatibility both in soft tissue and bone, although its long-term stability as well as its stability under function should further be examined.

树脂羟基磷灰石对骨反应的组织学研究。
树脂-羟基磷灰石是利用羟基磷灰石(HAP)的生物活性和树脂(Bis-GMA)的可塑性的优点而开发的。它由75%的HAP、15%的Bis-GMA和10%的石英增强填料组成。将树脂- hap测试颗粒及其成分植入成年犬股骨皮下结缔组织。术后12周组织学观察显示,每个颗粒被纤维结缔组织包围,几乎没有炎症细胞。HAP周围的纤维层厚度相对较薄,而Bis-GMA和Resin-HAP周围的纤维层厚度存在一定差异。考虑到我们之前的数据,我们认为Resin-HAP在软组织和骨骼中都具有生物相容性,但其长期稳定性和功能稳定性有待进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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