Anti-retroviral therapy adherence and its determinants among adult patients living with HIV/AIDS in South West Ethiopia: a facility-based cross sectional study

Gaziantep Medical Journal Pub Date : 1900-01-01 DOI:10.5455/GMJ-30-43192

Mekonnen Aragaw Ejigu, S. Ahmed, Mohammed A Mohammed

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引用次数: 6

Abstract

Adherence to anti-retroviral therapy (ART) regimen is essential for successful treatment and sustained viral control. Optimal adherence is the compliance to ART that achieves a sustained plasma drug concentration that suppresses viral replication. The objective of this study is to assess ART adherence and its determinants at Agaro Health Center ART Clinic, South Western Ethiopia. Facility-based cross sectional study was conducted from June 9-29, 2011. Patients were interviewed to collect adherence related information by using pretested semi-structured questionnaire. Subsequent charts of prescribed medications were reviewed using a pretested data collection format. A total of 209 respondents were included in the study, of which 127 (60.8%) were females and 82 (39.2%) were males. The average adherence rate was 98.1% among males and 99.5% among females. The overall average adherence rate among the respondents was 98.8%. One hundred sixty one (77.0%) respondents had a 100% adherence rate, 15 (7.2%) patients had a 93.3% adherence rate and the remaining 33 (15.8%) patients had adherence rate between 95 and 98% on average. The common reasons for missing of the prescribed doses were forgetting 27 (39.7%), being too busy 20 (29.4%), away from home 17 (25.0%) and being extremely ill 4 (5.9%). Of all the variables, sex, living alone, monthly income, use of stimulants and medications in addition to ART were significantly associated with non-adherence. The

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埃塞俄比亚西南部艾滋病毒/艾滋病成年患者抗逆转录病毒治疗依从性及其决定因素:一项基于设施的横断面研究

坚持抗逆转录病毒治疗方案对于成功治疗和持续控制病毒至关重要。最佳依从性是抗逆转录病毒治疗的依从性，达到持续的血浆药物浓度，抑制病毒复制。本研究的目的是评估埃塞俄比亚西南部Agaro健康中心ART诊所的ART依从性及其决定因素。基于设施的横断面研究于2011年6月9日至29日进行。采用预测半结构化问卷对患者进行访谈，收集依从性相关信息。使用预先测试的数据收集格式审查处方药物的后续图表。共纳入209人，其中女性127人(60.8%)，男性82人(39.2%)。男性的平均依从率为98.1%，女性为99.5%。受访者的总体平均依从率为98.8%。161例(77.0%)患者的依从率为100%，15例(7.2%)患者的依从率为93.3%，其余33例(15.8%)患者的依从率平均在95 ~ 98%之间。错过处方剂量的常见原因是忘记27例(39.7%)、太忙20例(29.4%)、不在家17例(25.0%)和重病4例(5.9%)。在所有变量中，性别、独居、月收入、兴奋剂的使用以及除抗逆转录病毒治疗外的药物治疗与不坚持治疗显著相关。的

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Gaziantep Medical Journal

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