{"title":"Perinatal factors associated with neural tube defects (anencephaly [correction of anancephaly], spina bifida and encephalocele).","authors":"A J Ogata, L Camano, D Brunoni","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The objective of the present study was to determine the presence of risk factors for the occurrence of neural tube defects. Data for 33,535 births which occurred at Hospital do Servidor Público Estadual de São Paulo from July 1973 to December 1986 were collected in a prospective manner as recommended by \"Estudo Colaborativo Latino-Americano de Malformações Congênitas\" (ECLAMC, Collaborative Latin American Study on Congenital Malformations). Twenty-six cases of neural tube defects were detected (0.77/1000 births). Of these, 11 were cases of spina bifida (0.39/1000 births), 9 of anencephaly (0.27/1000 births) and 6 of encephalocele (0.18/1000 births). We observed a higher frequency of polyhydramnios, premature labor, Apgar scores of less than 7 at the first and fifth minutes, low birth weight and intrauterine growth retardation.</p>","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 4","pages":"147-51"},"PeriodicalIF":0.0000,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista paulista de medicina","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The objective of the present study was to determine the presence of risk factors for the occurrence of neural tube defects. Data for 33,535 births which occurred at Hospital do Servidor Público Estadual de São Paulo from July 1973 to December 1986 were collected in a prospective manner as recommended by "Estudo Colaborativo Latino-Americano de Malformações Congênitas" (ECLAMC, Collaborative Latin American Study on Congenital Malformations). Twenty-six cases of neural tube defects were detected (0.77/1000 births). Of these, 11 were cases of spina bifida (0.39/1000 births), 9 of anencephaly (0.27/1000 births) and 6 of encephalocele (0.18/1000 births). We observed a higher frequency of polyhydramnios, premature labor, Apgar scores of less than 7 at the first and fifth minutes, low birth weight and intrauterine growth retardation.
本研究的目的是确定神经管缺损发生的危险因素的存在。根据“Estudo colativo Latin - americano de Malformações Congênitas”(ECLAMC，拉丁美洲先天性畸形合作研究)的建议，以前瞻性的方式收集了1973年7月至1986年12月期间在Servidor Público Estadual de ss o Paulo医院出生的33,535例新生儿的数据。发现神经管缺陷26例(0.77/1000)。其中，脊柱裂11例(0.39/1000)，无脑畸形9例(0.27/1000)，脑膨出6例(0.18/1000)。我们观察到羊水过多、早产、第1分钟和第5分钟Apgar评分低于7分、低出生体重和宫内发育迟缓的发生率较高。
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