The management of pediatric brain tumors in a tertiary center.

Medical oncology and tumor pharmacotherapy Pub Date : 1992-01-01 DOI:10.1007/BF02987750

M Mandel, A Toren, G Findler, Y Neumann, G Kende, M Faibel, R Tadmor, H Brenner, A Sahar, B Ramot

{"title":"The management of pediatric brain tumors in a tertiary center.","authors":"M Mandel, A Toren, G Findler, Y Neumann, G Kende, M Faibel, R Tadmor, H Brenner, A Sahar, B Ramot","doi":"10.1007/BF02987750","DOIUrl":null,"url":null,"abstract":"<p><p>Between January 1982 and January 1990, 120 newly diagnosed pediatric patients were treated at The Chaim Sheba Medical Center. Sixty three (52.5%) tumors arose in the posterior fossa and 57 (47.5%) appeared supratentorially. A wide variety of histologic subtypes was seen, each requiring tumor-specific treatment. The modern imaging techniques-CT and MRI-offered better planning of operation, treatment and follow up. All children with highly malignant tumors were treated with combination chemotherapy besides the 'conventional radiotherapy'. Since 1987 the \"eight in one day\" protocol has been used extensively pre- and post-irradiation. Five-year survival, varied significantly according to tumor type, location and stage. The average delay from presentation of symptoms to diagnosis was 6 months. A multidisciplinary approach has been used in the treatment, rehabilitation and follow-up of these children. In this study, the results of treatment are presented and the role of chemotherapy is discussed.</p>","PeriodicalId":77257,"journal":{"name":"Medical oncology and tumor pharmacotherapy","volume":"9 4","pages":"159-64"},"PeriodicalIF":0.0000,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02987750","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical oncology and tumor pharmacotherapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/BF02987750","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Between January 1982 and January 1990, 120 newly diagnosed pediatric patients were treated at The Chaim Sheba Medical Center. Sixty three (52.5%) tumors arose in the posterior fossa and 57 (47.5%) appeared supratentorially. A wide variety of histologic subtypes was seen, each requiring tumor-specific treatment. The modern imaging techniques-CT and MRI-offered better planning of operation, treatment and follow up. All children with highly malignant tumors were treated with combination chemotherapy besides the 'conventional radiotherapy'. Since 1987 the "eight in one day" protocol has been used extensively pre- and post-irradiation. Five-year survival, varied significantly according to tumor type, location and stage. The average delay from presentation of symptoms to diagnosis was 6 months. A multidisciplinary approach has been used in the treatment, rehabilitation and follow-up of these children. In this study, the results of treatment are presented and the role of chemotherapy is discussed.

查看原文本刊更多论文

三级中心小儿脑肿瘤的处理。

1982年1月至1990年1月期间，在Chaim Sheba医疗中心治疗了120名新诊断的儿科患者。63例(52.5%)肿瘤出现在后窝，57例(47.5%)肿瘤出现在幕上。各种各样的组织学亚型被发现，每一个都需要肿瘤特异性治疗。现代影像技术- ct和mri为手术、治疗和随访提供了更好的计划。高度恶性肿瘤患儿除“常规放疗”外，均行联合化疗。自1987年以来，在辐照前后广泛使用了“一天8次”方案。5年生存率根据肿瘤类型、部位和分期有显著差异。从出现症状到诊断的平均延迟为6个月。在这些儿童的治疗、康复和后续行动中采用了多学科方法。在本研究中，介绍了治疗结果，并讨论了化疗的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Medical oncology and tumor pharmacotherapy

自引率

0.00%

发文量