The Relationship Between The Characteristics of COVID-19 Patients To Predict Mortality in The COVID-19 ICU Special Care

M. Taufik, D. W. Wijaya, A. Lubis
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Abstract

Introduction: The SARS-CoV-2 epidemic is sweeping the world with several waves of infections continuing. In some COVID-19 patients, this condition can develop into ARDS (acute respiratory distress syndrome) which requires ICU care with a mortality rate of 50-65 and the need for mechanical ventilation reaches 97%. The aim of this research was to know characteristics of COVID-19 patients to predict mortality in the Negative Pressure Isolation Room COVID 19 ICU at H. Adam Malik General Hospital Method: Retrospective research method with secondary data sources of COVID-19 Negative Pressure Isolation Room ICU (RITN) patients at RSUP H. Adam Malik Medan for the period May 2021 – July 2021.The data collected was in the form of patient data including name, gender, age, medical record number, comorbidities, NLR, D-Dimer, Fibrinogen, PF ratio, use of oxygen supplementation, and length of ICU stay. Chi Square statistical analysis was used for categorical data, while the T-test or Mann Whitney was used for numerical data. Then between the variables an ANOVA test was carried out to assess the comparison of clinical characteristics with mortality. Results: The results of this study indicate a higher mortality rate in women41 people (57.7%), 56-65 years age group 26 people (36.6%), patients using ventilators 51 people (71.8%), comorbid hypertension 33 people (46.5%) ), Moderate PF Ratio were 44 people (62%) and Length of stay <10 days were 55 people (77.5%). The mean fibrinogen value in COVID-19 patients who died was 658.96 ± 674.98, as well as the D-dimer value of 658.96 ± 674.98 and NLR of 11.06 ± 3.23 which showed a significant increase compared to patients Survivors of COVID-19 (p<0.05). Conclusion: A significant relationship was found between gender, age, breathing apparatus, D-dimer, Fibrinogen, NLR and length of stay with mortality of COVID-19 patients treated in the COVID Negative Pressure Room (RITN) ICU
COVID-19患者特征与预测重症监护室病死率的关系
SARS-CoV-2疫情正在席卷全球,几波感染仍在继续。在一些COVID-19患者中,这种情况可发展为ARDS(急性呼吸窘迫综合征),需要ICU护理,死亡率为50-65,机械通气需求达到97%。本研究的目的是了解H. Adam Malik综合医院负压隔离室COVID-19 ICU患者的特征,以预测其死亡率。方法:回顾性研究方法,采用二手数据来源的RSUP H. Adam Malik Medan医院2021年5月至2021年7月期间COVID-19负压隔离室ICU (RITN)患者。收集的数据采用患者资料的形式,包括姓名、性别、年龄、病历号、合并症、NLR、d -二聚体、纤维蛋白原、PF比、补氧使用情况、ICU住院时间。分类资料采用卡方统计分析,数值资料采用t检验或Mann Whitney检验。然后在变量之间进行方差分析,以评估临床特征与死亡率的比较。结果:本组患者死亡率较高:女性41例(57.7%),56 ~ 65岁26例(36.6%),使用呼吸机51例(71.8%),合并高血压33例(46.5%),中度PF率44例(62%),住院时间<10天55例(77.5%)。死亡患者的平均纤维蛋白原值为658.96±674.98,d -二聚体值为658.96±674.98,NLR为11.06±3.23,与存活患者相比均有显著升高(p<0.05)。结论:性别、年龄、呼吸器、d -二聚体、纤维蛋白原、NLR、住院时间与COVID-19负压室(RITN) ICU收治的COVID-19患者死亡率有显著相关
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