Compared Levels of Specific Divalent Trace Elements in Hyperlipidemia and Hepatitis Sera Patients

H. Soran, Dler. M. Salh, A. Arif
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Abstract

Patients with hepatitis infection can also have hyperlipidemia. Sera of both hepatitis (40) and hyperlipidemia (40) were collected from the central lab of Sulaimaniyah-Kurdistan region/ Iraq. Age, sex, duration of infection, medication used and lipid profile using computerized database program, as characteristics information of patients were done.  The levels of Cr, Cu, Zn, Mn, V and Se were determined in sera of both patients and compared with healthy controlled (n=30), using Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES). Hepatitis samples yielded concentration in ppb of (7.34±0.01) Cr, (171.7±2.51) Cu, (138±3.41) Zn, (1.309±0.99) Mn, (184.7±6.12) V and (218.9±3.14) Se respectively, while hyperlipidemia samples yielded concentration (ppb) of (5.22±0.45) Cr, (197.01±2.34) Cu, (160.3±4.01) Zn, (0.068±1.91) Mn, (247.01±0.65) V and (185.5±3.11) Se respectively. Controlled samples reflects the following concentrations (ppm),  (5.324±1.34) Cr, (131.2±4.34) Cu, (216.6±0.83) Zn, (0.024±1.75) Mn, (235.3±0.18) V and (223.2±3.15) Se  respectively.The aim of the study focused on evaluating metal ions physiological role in the body, and as liver was responsible for synthesizing lipid , thus lipid profiles where suggested to be investigated along the study. Key words: hepatitis, hyperlipidemia, trace elements, ICP-OES technique
高脂血症和肝炎患者血清中特异二价微量元素水平的比较
肝炎感染的患者也可能有高脂血症。肝炎(40例)和高脂血症(40例)血清采集于苏莱曼尼亚-库尔德斯坦地区/伊拉克中心实验室。采用计算机化数据库程序对患者的年龄、性别、感染持续时间、用药情况、血脂等特征信息进行统计。采用电感耦合等离子体发射光谱法(ICP-OES)测定两例患者血清中Cr、Cu、Zn、Mn、V和Se的水平,并与健康对照(n=30)进行比较。肝炎样品的浓度ppb分别为(7.34±0.01)Cr、(171.7±2.51)Cu、(138±3.41)Zn、(1.309±0.99)Mn、(184.7±6.12)V和(218.9±3.14)Se,高脂血症样品的浓度ppb分别为(5.22±0.45)Cr、(197.01±2.34)Cu、(160.3±4.01)Zn、(0.068±1.91)Mn、(247.01±0.65)V和(185.5±3.11)Se。对照样品的浓度分别为(ppm)(5.324±1.34)Cr、(131.2±4.34)Cu、(216.6±0.83)Zn、(0.024±1.75)Mn、(235.3±0.18)V和(223.2±3.15)Se。本研究的目的是评估金属离子在体内的生理作用,由于肝脏负责脂质合成,因此建议在研究过程中对脂质谱进行调查。关键词:肝炎;高脂血症;微量元素
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