Pathogenetic justification of the use of criteria for determining the lifespan and age of wound caused by mechanical damage

A. Antonov, M. Klymenko, S. Tatarko, O. Herasymenko, Natalia Surhai, Volodymyr Shilan, Tetiana Uzbek
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Abstract

The aim of the study is detailed analysis of the literature on the existing methods for determining the lifetime and inflicting of mechanical damage. It was found that the existing methods have very large discrepancies in assessing the infliction of damage. The use of the same research methods by different researchers has lead to results that may differ. This can lead to obtaining insufficiently substantiated or even erroneous conclusions about the infliction of mechanical damage. The authors explain this by the fact that the body reacts to damage by the development of a typical pathological process – inflammation. Forensic methods that exist for determining the age of wound are aimed at obtaining an expert assessment of individual manifestations of the pathogenesis of inflammation by morphological, biochemical and immunological methods. Determination of the age of wound is actually the determination of a specific stage in the pathogenesis of inflammation, which is observed at the time of the examination and the timing of the development, which is known from the literature. Taking into account the stages of the pathogenesis of inflammation as a typical pathological process, in the area of tissue damage makes it possible to more accurately determine the duration of the infliction of mechanical damage. The individual reactivity of the organism, which determines the features of the course of any typical pathological process, will determine the individual timing of the development of certain morphological, biochemical and immunological changes in the area of damage.  
确定机械损伤引起的伤口寿命和年龄标准的病理学依据
本研究的目的是详细分析现有的确定寿命和造成机械损伤的方法的文献。研究发现,现有的方法在评估造成的损害方面存在很大的差异。不同的研究人员使用相同的研究方法可能会导致不同的结果。这可能导致关于机械损伤的结论不充分,甚至是错误的。作者解释说,身体对损伤的反应是一种典型的病理过程——炎症。现有用于确定伤口年龄的法医方法旨在通过形态学、生化和免疫学方法对炎症发病机制的个体表现进行专家评估。伤口年龄的确定实际上是确定炎症发病的特定阶段,这是在检查时观察到的,也是从文献中知道的发展时间。考虑到炎症发病的阶段作为典型的病理过程,在组织损伤领域可以更准确地确定机械损伤的持续时间。机体的个体反应性决定了任何典型病理过程的特征,也将决定损伤区域发生某些形态、生化和免疫变化的个体时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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