Voltage and Current Bi-Mode Stimulation Circuit of Low-Power Deep Brain Stimulator

Zhaonan Qin, Xiang Chen, Hua Jin, Jin Li
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Abstract

In order to treat patients with advanced L-Dopamine-reactive Parkinson's disease whose symptoms cannot be effectively controlled by drugs, a stimulation circuit of a deep brain stimulator with bi-modes of voltage and current was designed and implemented. The amplitude of stimulation pulse is controlled by an adjustable stable voltage output circuit, an adjustable constant current source and an I-V Converter circuit, the frequency and width of stimulation pulse are controlled by an electronic switch, and the stimulation pulse output function for deep brain nucleus is realized by biphasic current stimulation pulses and charge-balanced voltage stimulation pulses.
低功率深部脑刺激器的电压电流双模刺激电路
为了治疗药物无法有效控制症状的晚期左旋多巴胺反应性帕金森病患者,设计并实现了一种电压电流双模深部脑刺激器的刺激回路。刺激脉冲的幅值由可调稳压输出电路、可调恒流源和I-V变换器电路控制,刺激脉冲的频率和宽度由电子开关控制,通过双相电流刺激脉冲和电荷平衡电压刺激脉冲实现对脑深部核的刺激脉冲输出功能。
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