Optimization of Vaccine Production in Workshop Based on Genetic Algorithm

Danhong Wu, Can Huang, Huazhou Zeng, Yujing Zhao
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Abstract

In the face of some infectious diseases raging all over the world, the efficiency of vaccine production directly affects the ability of medical staff to rescue patients and the timeliness of global epidemic prevention. Therefore, it is of great significance to establish an optimal planning model from the production source to minimize the time required for vaccine production without affecting the quality of vaccine production. This paper analyzes and discusses the problem of vaccine production from two aspects. Firstly, under ideal conditions, without considering the impact of vaccine production time, based on the average time of producing each box of vaccine at each station, a scheduling optimization model with multi-objective constraints is established, and then the flow shop scheduling model (FSP) of genetic algorithm is used to solve it. We estimate that the gene assignment adopts a classical roulette algorithm, the gene crossover part adopts the partial mapping crossover algorithm, and the gene mutation step uses the gene reverse order algorithm to simulate the operation of the stack. In practice, the time required to produce each vaccine at each station is random. Bring in the normal probability distribution function, improve the genetic algorithm and shorten the total time by 5%.
基于遗传算法的车间疫苗生产优化
面对一些肆虐全球的传染病,疫苗生产效率的高低直接影响到医护人员抢救病人的能力和全球防疫的及时性。因此,在不影响疫苗生产质量的前提下,从生产源头建立疫苗生产最优规划模型具有重要意义。本文从两个方面对疫苗生产问题进行了分析和探讨。首先,在理想条件下,在不考虑疫苗生产时间影响的情况下,以每个工位生产每箱疫苗的平均时间为基础,建立了多目标约束的调度优化模型,并利用遗传算法的流水车间调度模型(FSP)对其进行求解。我们估计基因分配采用经典轮盘赌算法,基因交叉部分采用部分映射交叉算法,基因突变部分采用基因倒序算法模拟堆栈操作。实际上,在每个站点生产每种疫苗所需的时间是随机的。引入正态概率分布函数,改进遗传算法,使总时间缩短5%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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