Combined Cortico-cancellous and cancellous fresh paternal allograft in defect post resection of benign bone tumors of long bones in children, review of literatures with two cases study

Dr. Ahmad Shakir Turkey Alawadi, Dr. Yaman Ahmad Kadhim, Dr. Hamed Gata Hassen
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Abstract

We study the use of paternal fresh allograft in pediatric massive bony loss (post benign bone tumor resection) with a graft type of combined Cortico-cancellous and cancellous bone, with a good result of rapid and complete union with no recurrence with in 2years of follow up, with no any sign of local or systemic rejection. Study of 2 patients, one of an osteoblastoma in female of 9 years old in shaft femur and the second case was an aneurysmal bone cyst (ABC) in male of 11 years old in distal third of fibula where in both do enbloc resection for a big bony lesions in such young age group, the defect was 8cm in the female and 9 cm in male case. We reconstruct these defects by the fresh non-frozen paternal allograft which still not widely used method and we add the use of Combined Cortico-cancellous and cancellous bone graft of iliac crest area which was not used or mentioned before in literatures and we do internal fixation in both and we wash the graft 2 times pre and post application in the gap with a normal saline for each case, follow up by monthly x-ray films till healing. Was conclusive and more than expected regarding healing rate and union which was 6month in female case and 5 month in male and no complication in such big bony graft mass. In Followed up of 2 years no recurrance was seen and both donors and without any disability nor morbidity.
皮质-松质联合松质新鲜父本同种异体移植治疗儿童长骨良性骨肿瘤术后缺损,附2例文献复习
我们研究了父亲新鲜同种异体骨移植在小儿大面积骨丢失(良性骨肿瘤切除后)中的应用,采用皮质松质骨和松质骨联合移植,在2年的随访中获得了快速完全愈合的良好结果,没有复发,没有任何局部或全身排斥反应的迹象。研究了2例患者,1例为9岁的女性股骨骨干成骨细胞瘤,2例为11岁的男性腓骨远端三分之一动脉瘤性骨囊肿(ABC),两例患者均对该年龄组的大骨病变进行了包切术,缺损女性为8cm,男性为9cm。我们用新鲜的非冷冻的父本同种异体骨移植重建这些缺陷,这种方法目前还没有被广泛使用,我们还使用了皮质-松质骨和松质骨联合移植髂骨,这在以前的文献中没有被使用或提到过,我们在这两种情况下都进行了内固定,我们在每个病例中使用生理盐水冲洗移植前后2次,随访每月x线片,直到愈合。在愈合率和愈合方面是结论性的,超出预期,女性病例为6个月,男性病例为5个月,无并发症。随访2年无复发,供者无残疾,无发病。
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