Open arch surgery in the redo setting. Contemporary outcomes.

A. Vekstein, G. Hughes, E. Chen
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Abstract

BACKGROUND Aortic arch reconstruction after prior cardiac surgery is technically complex, especially after proximal aortic surgery. While multiple surgical adaptations in the redo setting have been described, traditional open reconstruction remains the most common approach with significant variability in outcomes in prior reports. This study describes institutional adaptations to surgical technique and perioperative care and assesses operative and long-term outcomes after redo-aortic arch repair in the modern era. METHODS Patients undergoing hemi- or total arch reconstruction after prior cardiac surgery (2005-2022) were identified from a prospectively maintained institutional database. Strategic adaptations in approach over the study interval included a shift towards Type II hybrid arch repair for patients with "mega-aorta," redo-cannulation of the axillary artery when necessary, and adoption of transfusion and early extubation protocols. Outcomes of interest included 30-day/in-hospital adverse events and actuarial long-term overall and aorta-specific survival. RESULTS The study cohort included 214 patients undergoing hemi-arch (n=154, 72%) or total arch (n=60, 28%) after prior cardiac surgery (50% prior proximal aortic surgery). Surgical indications included degenerative aneurysm (47%, n=101), residual arch dissection after prior type A repair (29%, n=61), acute or chronic type A dissection (18%, n=39) or other (6%, n=13). 30-day/in-hospital mortality was 6% (5% hemi-arch; 10% total arch) and stroke was 3% (3% hemi-arch; 2% total arch). At median follow-up of 56 months, overall 5- and 10-year survival was 76% and 58% (hemi-arch: 81%, 62%; total arch: 63%, 43%); aorta-specific survival was 91% and 90% (hemi-arch: 96%, 94%; total arch: 79%, 79%). CONCLUSIONS In this modern single-institution series, a systematic approach to redo-arch repair yields excellent operative outcomes and late aorta-specific survival. Reduced late overall survival reflects the comorbidity burden of this population. Open reconstruction continues to play an important role in reoperative arch repair in the modern era.
开放弓手术在重做设置。当代的结果。
背景先前心脏手术后主动脉弓重建在技术上是复杂的,特别是近端主动脉手术后。虽然在重做的情况下有多种手术适应,但传统的开放式重建仍然是最常见的方法,在以前的报道中结果有很大的差异。本研究描述了机构对手术技术和围手术期护理的适应,并评估了现代主动脉瓣弓修复后的手术和长期结果。方法从前瞻性维护的机构数据库中确定既往心脏手术后接受半或全弓重建的患者(2005-2022)。在研究期间的策略调整包括对“大主动脉”患者转向II型混合弓修复,必要时重新插管腋窝动脉,采用输血和早期拔管方案。关注的结局包括30天/住院不良事件和精算长期总生存率和主动脉特异性生存率。结果研究队列包括214例既往心脏手术(50%既往主动脉近端手术)后接受半弓(n=154, 72%)或全弓(n=60, 28%)的患者。手术指征包括退行性动脉瘤(47%,n=101),先前A型修复后残留弓夹层(29%,n=61),急性或慢性A型夹层(18%,n=39)或其他(6%,n=13)。30天/住院死亡率为6%(半拱5%;全弓10%),卒中3%(半弓3%;总拱高2%)。中位随访56个月时,5年和10年总生存率分别为76%和58%(半弓期:81%,62%;总弓度:63%,43%);主动脉特异性生存率分别为91%和90%(半弓:96%,94%;总弓度:79%,79%)。结论:在这个现代单机构的系列研究中,系统的研究弓修复方法可获得良好的手术效果和晚期主动脉特异性生存率。晚期总生存率降低反映了这一人群的合并症负担。开放重建在现代弓修复中继续发挥着重要作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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