Review of Modifiable Risk Factors for Gout in Asia

Abstract

Gout is the most common inflammatory arthritis in the world, including in the Asia region. Gout is a debilitating, yet preventable disease. The general principle of gout prevention is to regulate circulating UA concentration and other related comorbidities. Identifying gout modifiable risk factors is paramount in gout prevention. This review aims to explain modifiable risk factors for gout, especially in the Asia region. Apart from urate-lowering therapy, modifying gout risk factors consisted of a low-purine diet, mild to moderate exercise, adequate sleep, elimination of smoking exposure, and regulation of comorbidities such as hypertension, obesity, metabolic syndrome, and kidney diseases, lowered the risk of hyperuricemia and gout in Asian population.