Deepak Khobragde, A. Kotha, K. Ravalika, Richa Gupta, P. Kumar
{"title":"Oro-dispersible tablets of ayurvedic powder for improving taste, compliance, ease and accuracy of administration","authors":"Deepak Khobragde, A. Kotha, K. Ravalika, Richa Gupta, P. Kumar","doi":"10.7439/IJASR.V2I6.3458","DOIUrl":null,"url":null,"abstract":"Most of the ayurvedic medicines are in the form of powder. Being in powder form the administration of accurate dose with ease is a problem. They may have some kind of unacceptable bitter taste. Furthermore it needs water or honey for administration and chances of spoilage and waste are more. Oro-dispersible tablet which rapidly disintegrating in mouth will be the best remedy for efficient use of ayurvedic powders. The aim of this study was to formulate oro-dispersible tablets of ayurvedic polyherbal powder Talisadi. Talisadi is a traditional Ayurvedic powder preparation well known and effective in various disorders of respiratory and digestive system. Using various excipients like super-disintegrants and sweeteners, different formulation of polyherbal drug Talisadi were formulated by direct compression method. The acceptable formulation, among all the developed formulations of oro-dispersible tablet was having a disintegrating time of 1 min and 10 sec and acceptable taste. Thus the study concludes that formulation of oro-dispersible tablets of ayurvedic powder preparation can be a good option to enhance acceptability, efficiency and easy and accurate administration of powder ayurvedic preparations like Talisadi.","PeriodicalId":119953,"journal":{"name":"International Journal of Advances in Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Advances in Scientific Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7439/IJASR.V2I6.3458","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Most of the ayurvedic medicines are in the form of powder. Being in powder form the administration of accurate dose with ease is a problem. They may have some kind of unacceptable bitter taste. Furthermore it needs water or honey for administration and chances of spoilage and waste are more. Oro-dispersible tablet which rapidly disintegrating in mouth will be the best remedy for efficient use of ayurvedic powders. The aim of this study was to formulate oro-dispersible tablets of ayurvedic polyherbal powder Talisadi. Talisadi is a traditional Ayurvedic powder preparation well known and effective in various disorders of respiratory and digestive system. Using various excipients like super-disintegrants and sweeteners, different formulation of polyherbal drug Talisadi were formulated by direct compression method. The acceptable formulation, among all the developed formulations of oro-dispersible tablet was having a disintegrating time of 1 min and 10 sec and acceptable taste. Thus the study concludes that formulation of oro-dispersible tablets of ayurvedic powder preparation can be a good option to enhance acceptability, efficiency and easy and accurate administration of powder ayurvedic preparations like Talisadi.
大多数阿育吠陀药物都是粉末状的。在粉末状的情况下,容易给药是一个问题。它们可能有某种令人难以接受的苦味。此外,它需要水或蜂蜜来管理,腐败和浪费的可能性更大。口服分散片在口腔中迅速崩解,是有效使用阿育吠陀粉末的最佳补救措施。本研究的目的是研制阿育吠陀多草药粉的口服分散片。Talisadi是一种传统的阿育吠陀粉末制剂,众所周知,对各种呼吸和消化系统疾病有效。采用超崩解剂、甜味剂等辅料,采用直接加压法制备了不同配方的复方药塔利沙帝。所研制的口腔分散片的可接受配方为崩解时间为1 min 10 s,口感可接受。因此,制备阿育吠陀粉末制剂的口服分散片是提高阿育吠陀粉末制剂的可接受性、效率和方便准确给药的一个很好的选择。