Fluorescent and photodynamic properties of infrared photosensitizer bacteriochlorophyllide-serine

International Conference on Laser and Laser Information Technologies Pub Date : 2004-06-21 DOI:10.1117/12.563144

I. Meerovich, I. Kubasova, G. A. Meerovich, A. A. Stratonnikov, S. Demura, A. Brandis, V. Rosenbach‐Belkin, A. Scherz

引用次数: 2

Abstract

The study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine. The peculiarities of its fluorescence under different laser excitation conditions, dynamics of concentration and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue deoxygenation during tumor irradiation were performed. It was shown that bacteriochlorophyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.

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红外光敏剂细菌叶绿素丝氨酸的荧光和光动力学性质

研究了近红外光敏剂细菌叶绿素丝氨酸的荧光和光动力学特性。研究了其在不同激光激发条件下的荧光特性、浓度动力学和积累选择性。对小鼠进行了光动力治疗，并对肿瘤照射过程中组织脱氧情况进行了研究。结果表明，细菌叶绿酰丝氨酸是一种有效的光敏剂，用于肿瘤的PDT和荧光诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International Conference on Laser and Laser Information Technologies

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