Acute Angioedema in a Patient on Long-term Angiotensin Converting Enzyme Inhibitor Following Oral Surgery: A Case Report

C. Awoniyi, Steven Yannaras, Julia M. Bauerfeind
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Abstract

A relatively common side effect of angiotensin converting enzyme inhibitors (ACE-I), used for the treatment of high blood pressure, is angioedema. Whereas, angioedema due to ACE-I usually appear during the first few days or weeks of treatment, delayed onset, years after initiation of treatment is often unrecognized and can lead to life-threatening adverse events. We present a case report of rapidly progressive tongue swelling a few hours following oral surgery in a 62-year-old male who had been on ACE-I therapy for seven years. Prompt recognition and treatment prevented an impending respiratory compromise that could have been catastrophic.
口腔手术后长期服用血管紧张素转换酶抑制剂的急性血管性水肿1例报告
用于治疗高血压的血管紧张素转换酶抑制剂(ACE-I)的一个相对常见的副作用是血管性水肿。然而,由于ACE-I引起的血管性水肿通常在治疗的最初几天或几周内出现,延迟发作,在开始治疗后数年往往不被发现,并可能导致危及生命的不良事件。我们报告了一个病例报告,在口腔手术后几小时内,一位62岁的男性患者接受了7年的ACE-I治疗。及时的识别和治疗阻止了可能造成灾难性后果的迫在眉睫的呼吸损害。
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