Transcriptional repression by methylation of CpG.

R Meehan, J Lewis, S Cross, X Nan, P Jeppesen, A Bird
{"title":"Transcriptional repression by methylation of CpG.","authors":"R Meehan,&nbsp;J Lewis,&nbsp;S Cross,&nbsp;X Nan,&nbsp;P Jeppesen,&nbsp;A Bird","doi":"10.1242/jcs.1992.supplement_16.2","DOIUrl":null,"url":null,"abstract":"<p><p>Methylated DNA in mammals is associated with transcriptional repression and nuclease resistant chromatin. In this review we discuss how these effects may be mediated by proteins that bind to methylated DNA.</p>","PeriodicalId":77195,"journal":{"name":"Journal of cell science. Supplement","volume":"16 ","pages":"9-14"},"PeriodicalIF":0.0000,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1242/jcs.1992.supplement_16.2","citationCount":"91","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cell science. Supplement","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1242/jcs.1992.supplement_16.2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 91

Abstract

Methylated DNA in mammals is associated with transcriptional repression and nuclease resistant chromatin. In this review we discuss how these effects may be mediated by proteins that bind to methylated DNA.

CpG甲基化的转录抑制作用。
哺乳动物DNA甲基化与转录抑制和核酸酶抗性染色质有关。在这篇综述中,我们讨论了这些影响是如何通过结合甲基化DNA的蛋白质介导的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信