Postoperative Lumbar Spondylodiscitis Following Transforaminal Endoscopy and Outcomes of Transforaminal Lumbar Interbody Fusion

A. Krishnan, Vikrant Chauhan, D. Degulmadi, S. Mayi, Raviranjan Rai, Mirant R Dave, Shivakumar A Bali, Pranav Charde, Abhijith K Anil, Pretty Krishnan, B. Dave
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Abstract

Objective: To describe the presentation spectrum of postoperative spondylodiscitis (POS e ) following transforaminal endoscopic lumbar discectomy and to report the outcomes of transfo-raminal lumbar interbody fusion (TLIF). Methods: This study analyzed all patients with the classic features of POS e who underwent index surgery elsewhere and presented to us. They had not responded to conservative care for 3 weeks and were operated further with open TLIF. The treatment response was judged by the declining values of inflammatory markers, improvements in mobility, and decreases in pain. Patients’ outcomes were analyzed using a visual analogue scale (VAS), the Oswestry Disability Index (ODI), and the occurrence of complications. Radiological outcomes were assessed by fusion and implant stability. The spectrum of the demographic presentation was analyzed. PubMed was searched to find the incidence of POS e and the spectrum of organisms involved. Results: Fifteen patients were operated primarily by interventionalists and four by surgeons among 19 POS e patients who finally underwent TLIF at Stavya Spine Hospital & Research Institute. Organism culture positivity was found in 10 and no culture results were present in 9 cases. All TLIF cases had a follow-up of 52.94±13.66 months (range, 28–71 months). The preoperative back pain VAS improved from 9.47±0.61 (8–10) to 0.42±0.50 (0–1). The leg pain VAS improved from 5.78±4.19 (6–10) to 0.52±0.61 (0–1). The preoperative ODI improved from 87.01±7.70 (73.33–97.79) to 7.36±8.14 (0–26.67). No major complications occurred. Cure of infection and stable reconstruction with fusion were achieved in all patients. Conclusion: POS e has a very low reported incidence. Standardization of training and sterilization would further reduce its incidence. However, aggressive early TLIF in patients with nonresponding POS e produces beneficial results.
经椎间孔内窥镜术后腰椎椎间盘炎和经椎间孔腰椎体间融合术的结果
目的:描述经椎间孔内窥镜下腰椎间盘切除术后脊柱炎(POS e)的表现谱,并报告经椎间孔腰椎椎体间融合(TLIF)的结果。方法:本研究分析了所有在其他地方接受过指数手术的具有典型特征的POS e患者。保守治疗3周无反应,继续行开放性TLIF手术。治疗反应是通过炎症标志物的下降、活动能力的改善和疼痛的减轻来判断的。采用视觉模拟评分(VAS)、Oswestry残疾指数(ODI)和并发症发生情况对患者的预后进行分析。放射学结果通过融合和种植体稳定性评估。分析了人口统计学表现的频谱。PubMed检索了POS e的发病率和涉及的生物谱。结果:在Stavya脊柱医院和研究所最终行TLIF的19例POS患者中,15例由介入医师主刀,4例由外科医生主刀。生物培养阳性10例,无培养结果9例。所有TLIF病例随访时间为52.94±13.66个月(28 ~ 71个月)。术前腰痛VAS评分由9.47±0.61(8-10)分改善至0.42±0.50(0-1)分。腿部疼痛VAS评分由5.78±4.19(6-10)分改善至0.52±0.61(0-1)分。术前ODI由87.01±7.70(73.33-97.79)改善至7.36±8.14(0-26.67)。无重大并发症发生。所有患者感染治愈,融合重建稳定。结论:POS的发病率极低。培训和消毒的标准化将进一步减少其发生率。然而,在无应答性POS患者中,积极的早期TLIF会产生有益的结果。
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