Comparison of the Application of Different Fluoride Supplements on Enamel Demineralization Adjacent to Orthodontic Brackets: An In Vitro Study

Abstract

Background: White spot lesion is considered as one of the main problems in the orthodontic treatment. Brackets used in fixed orthodontic treatment create an environment that provides enamel demineralization. Objectives: Theobjectiveof thecurrentstudywastoperformaninvitrostudytocomparedifferentapplicationsof fluoridesupple-mentsonenameldemineralizationadjacenttoorthodonticbracketsandfinallytounderstandthebestsupplementtorecommend the patients. Methods: One hundred and twenty extracted caries-free human premolar teeth were randomly assigned into six groups: group 1: Controlgroup,group2: Fluoridetoothpaste,group3: Fluoridetoothpaste/mouthrinse,group4: Fluoridetoothpaste/vanish,group 5: Fluoridetoothpaste/gelandgroup6: Fluoridetoothpaste/foam. Afterbondingthebracketstotheteeth,thefluoridesupplements were applied based on each group above, except the control group. Then all the specimens were cycled for 30 days in demineralization solution for 8 hours a day, rinsed, placed in artificial saliva for 4 hours a day, brushed (except the control group), and put back to artificial saliva for 12 hours. DIAGNOdent laser fluorescence was used to quantify the demineralization changes. Results: Significantdifferencesexistedbetweenallfluoride-containinggroupsandcontrolgroup. Analysesof theresultsshoweda significantdifferencebetweencontrolgroupandtherest5treatmentgroups(P< 0.001). Othersignificantdifferenceswerebetween groups 2/5, 3/5, 2/4 and 5/6 (P < 0.05). There was no significant difference among the other groups (P > 0.05). Conclusions: Accordingtotheresults,allfluoridesupplementscouldbeusedduringorthodontictreatmenttodecreasetheenamel demineralization. It has been illustrated that fluoride-containing toothpaste and mouth rinse is better than no fluoride treatment but is not effective as well as fluoride gel and varnish.