Fasia latanın neokondrogenezis üzerine olan etkilerinin tavşan modelinde araştırılması

Journal of Medical Updates Pub Date : 2014-06-01 DOI:10.2399/JMU.2014002002

Şengül Yılmaz, Özge Bilkay, İsmail Özdemir, Arzu Avcı, Işıl Adadan Güvenç

{"title":"Fasia latanın neokondrogenezis üzerine olan etkilerinin tavşan modelinde araştırılması","authors":"Şengül Yılmaz, Özge Bilkay, İsmail Özdemir, Arzu Avcı, Işıl Adadan Güvenç","doi":"10.2399/JMU.2014002002","DOIUrl":null,"url":null,"abstract":"Objective: The impact of fascia lata on neochondrogenesis placed between both leaflets of the perichondrium after full thickness submucoperichondrial cartilage resection was investigated in a rabbit septum model. Methods: Twenty adult New Zealand rabbits were studied in two groups with equal number of animals in each group. Full thickness cartilage with an area of 1 cm² was resected to create a cartilage defect in all rabbits. Autogenous fascia lata was interposed between both leaflets of the perichondrium and the surgical field was closed (fascia lata group). Any material was not interposed between both leaflets of the perichondrium of the defective area (control group). Rabbits were sacrificed on postoperative 90th days and their septa were totally excised. Neochondrogenesis was investigated histopathologically with a light microscope. The preparations were evaluated as for thickness of newly formed cartilage (in mm), inflammatory reaction and presence of macroscopic perforation. Results: Thickness of the cartilage in the fascia lata group was significantly greater than that of the control group (M-W-U=15,000, p","PeriodicalId":162718,"journal":{"name":"Journal of Medical Updates","volume":"184 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Updates","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2399/JMU.2014002002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: The impact of fascia lata on neochondrogenesis placed between both leaflets of the perichondrium after full thickness submucoperichondrial cartilage resection was investigated in a rabbit septum model. Methods: Twenty adult New Zealand rabbits were studied in two groups with equal number of animals in each group. Full thickness cartilage with an area of 1 cm² was resected to create a cartilage defect in all rabbits. Autogenous fascia lata was interposed between both leaflets of the perichondrium and the surgical field was closed (fascia lata group). Any material was not interposed between both leaflets of the perichondrium of the defective area (control group). Rabbits were sacrificed on postoperative 90th days and their septa were totally excised. Neochondrogenesis was investigated histopathologically with a light microscope. The preparations were evaluated as for thickness of newly formed cartilage (in mm), inflammatory reaction and presence of macroscopic perforation. Results: Thickness of the cartilage in the fascia lata group was significantly greater than that of the control group (M-W-U=15,000, p

查看原文本刊更多论文

目的:在兔鼻中隔模型中，研究全层软骨下软骨切除术后软骨膜两小叶间阔筋膜对新软骨形成的影响。方法:将成年新西兰兔20只分为两组，每组等数。所有兔均切除1 cm²的全层软骨，形成软骨缺损。自体阔筋膜夹于软骨膜两小叶之间，术野闭合(阔筋膜组)。缺损区软骨膜的两个小叶(对照组)之间没有任何物质介入。术后第90天处死家兔，完全切除中隔。光镜下组织病理学观察新软骨形成。评估了新形成软骨的厚度(毫米)、炎症反应和宏观穿孔的存在。结果:阔筋膜组软骨厚度明显大于对照组(M-W-U= 15000, p

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Medical Updates

自引率

0.00%

发文量