[Microbicidal effect of Lautercide, a new disinfectant].

J Kneiflová, M Slosárek, V Melicherciková, J Paríková
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Abstract

The authors tested the effect of a new disinfectant Lautericide produced by Qualichem Co. Neratovice which contains as the active agent acetate amine of coconut acid. For experiments standard methods were used and standard strains for testing of the following microbial strains: St. aureus, E. coli, Ps. aeruginosa, Proteus vulgaris, Serratia marcescens, Candida albicans, spores of Bacillus subtilis, M. tuberculosis, M. fortuitum, M. avium. As a model virus E. coli bacteriophage OX 174 was used. In concentrations from 0.04% to 0.5% and exposures from 2 to 10 minutes Lautercide exerted a bactericidal and fungicidal action. On spores of B. subtilis the preparation was ineffective even in a 10% concentration and 32-minute exposure. Devitalization of mycobacteria occurred after 15 min. action of Lautercide on M. tuberculosis and M. fortuitum, in M. avium in a 10% concentration in 60 min. Lautercide is ineffective against small resistant viruses without an integument. It is recommended to use Lautercide in a 1% aqueous solution for a one-stage disinfection combined with cleaning in the health services, veterinary medicine and in the field of communal hygiene. Before cleaning objects contaminated with infectious material, 5% Lautercide with 30 min. exposure is recommended. In disinfection of objects contaminated with mycobacteria it is recommended to use a 5% solution with 10-minute exposure for M. tuberculosis and M. fortuitum and a 10% solution for M. avium with 60-minute exposure.

新型消毒剂Lautercide的杀菌效果
对Qualichem公司生产的以椰子酸醋酸胺为活性剂的新型杀菌剂进行了效果试验。实验采用标准方法和标准菌株检测以下微生物菌株:金黄色葡萄球菌、大肠杆菌、铜绿假单胞菌、普通变形杆菌、粘质沙雷菌、白色念珠菌、枯草芽孢杆菌孢子、结核分枝杆菌、福氏分枝杆菌、鸟分枝杆菌。以大肠杆菌噬菌体ox174为模型病毒。在浓度为0.04%至0.5%,暴露时间为2至10分钟的情况下,劳特杀菌剂具有杀菌和杀真菌的作用。对枯草芽孢杆菌孢子,即使在10%的浓度和32分钟的暴露是无效的。劳特杀菌剂对结核分枝杆菌和福氏分枝杆菌作用15分钟后发生失活,对禽分枝杆菌作用10%浓度60分钟后发生失活。劳特杀菌剂对没有被膜的小耐药病毒无效。建议在卫生服务、兽医和公共卫生领域使用1%的劳特杀菌水溶液进行一级消毒与清洁相结合。在清洁被传染性物质污染的物品之前,建议使用5%的劳特杀菌剂,暴露30分钟。在对被分枝杆菌污染的物体进行消毒时,建议使用5%的溶液对结核分枝杆菌和福氏分枝杆菌进行10分钟的消毒,使用10%的溶液对鸟分枝杆菌进行60分钟的消毒。
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