Screening of the defi ciency of glucose-6-phosphate dehydrogenase of newborn babies

Abstract

Deficiency of glucose - 6 - phosphate dehydrogenase (G6PD) - X - linked enzyme defect, which can manifest itself as hemolysis after acute infections or ingestionoxidants (salicylates and sulfonamides). Diagnosis is based on G6PD levels, although the test often gives a false negative result in the presence of acute hemolysis. Treatment is supportive. Since this pathology is X-linked, the complete clinical picture is observed in men and homozygous women; in heterozygous women, clinical manifestations are variable.