2022-RA-908-ESGO The importance of pathological ultrastaging for sentinel lymph nodebiopsy in cervical cancer, the final outcome of the Sentix study (CEEGOG-CX01; ENGOT-CX2; NCT02494063)

Abstract

2022-RA-908-ESGO Figure 1 Conclusion Pathological ultrastaging is a key component of the SLN concept in cervical cancer. It enables detection of additional 44% of patients with N1 (MAC, MIC) and almost all (91%) with ITC. The detection of positive SLN directly correlates with the intensity of ultrastaging. Four levels should become an international standard, which allows to detect over 90% of N1 (MAC, MIC). 2022-VA-920-ESGO ADRENAL GLAND RECURRENT CERVICAL CANCER TREATED BY MINIMALLY INVASIVE APPROACH Andrea Rosati, Camilla Certelli, Giulia Scaglione, Alessandro Baroni, Alex Federico, Filippo Maria Capomacchia, Pierfrancesco Greco, Francesco Fanfani, Giovanni Scambia, Valerio Gallotta. Policlinico Agostino Gemelli, Roma, Italy 10.1136/ijgc-2022-ESGO.70 Introduction/Background Recurrence of disease represents a clinical challenge in cervical cancer patients and the choice of the best treatment depends on previous therapy and site of recurrent tumor. The paraortic lymph nodes and the lungs were the extrapelvic areas more frequently involved, whereas adrenal gland involvement is rarely reported. Some reports confirmed the survival benefit of secondary radical surgery in confined recurrence, although this finding has been rarely investigated in the literature with only a few case series reported mostly focusing on lung metastases. Methodology Here a case of isolated adrenal gland cervical cancer recurrence in a 62-year-old woman is presented. Preoperative computed and emission tomography scans detected a nodule of 26 mm with increased uptake involving the medial lip of the right adrenal gland and a lymph node of 8 mm behind the inferior vena cava. A retrocaval lymphadenectomy and right adrenalectomy was performed. In this video we showed a minimally invasive approach tailored on the patient disease with the help of intraoperative ultrasound. Results We reached a residual tumor of zero with good operation times. No intra or postoperative complications occurred. Final histology confirmed the metastatic involvement of both the adrenal gland and the retrocaval lymph node by an undifferentiated carcinoma. After a multidisciplinary board evaluation, the patient underwent chemotherapy. Conclusion Minimally invasive surgery in selected patients with isolated extrapelvic cervical cancer recurrence is feasible and safe. Since radicality may be guaranteed by intraoperative imaging such as ultrasound, surgery can be tailored on the single patient and disease. 2022-RA-926-ESGO AWARENESS, ATTITUDES AND PRACTICES OF WOMEN IN RELATION TO CERVICAL CANCER SCREENING IN MAINLAND CHINA Sumeng Wang, Youlin Qiao. Department of Cancer Epidemiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Center for Global Health, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China 10.1136/ijgc-2022-ESGO.7