Verteporfin Photodynamic therapy with 5 aza-deoxy-cytidine for neo-adjuvant treatment of primary breast cancer: Results of pre-clinical investigations

Abstract

Primary breast cancer treatment relying on surgery with the use neo-adjuvant therapies has long been established treatment. Side effects from these and varying efficacy has lead to the search for novel therapies that may result in improved results. The use of Photodynamic therapy as a novel neo-adjuvant treatment alone and in combination with agents cytotoxic to breast cancer cells was investigated.