Highly sensitive TiO2 thin film matrix biosensor for glucose detection in blood

Abstract

Nanotechnology and bionanotechnology has opened new ways for fabricating sensors to detect gases, explosives or biological molecules. Biological molecule detection is very important for healthcare industry, food industry and in research. Nanostructured metal-oxides can be used to fabricate biosensors with high sensitivity, good response time and chemical stability for the detection of biological molecules by electrochemical oxidation. In this paper, we developed a nanostructured metal-oxide anatase TiO2 thin film as a sensing surface by using a new technique. The TiO2/SiO2/Si thin film matrix based glucose biosensor has good sensitivity, response time and selectivity. The phase modified anatase titania sensing thin film has been fabricated by biological technique using biological cells. The anatase TiO2 thin film was deposited on SiO2/Si at 28°C in presence of magnetic field. The high surface to volume ratio of TiO2 thin film showed excellent response to detect the glucose molecule. The results of time response studies of this biosensor show excellent sensitivity and rapid detection. The fabrication method of sensor for biomolecule detection is green and cost effective process for the development of sensing device for biosensing applications.