Laparoscopic surgery for early-stage endometrial cancer: Peri-operative outcomes and prognosis at Oji General Hospital

K. Mitsube, Maki Kanno, M. Nakatani, M. Kudo, E. Nomura
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Abstract

Objectives: The aims of this study were to report the feasibility of laparoscopic surgery for early-stage endometrial cancer and to assess the effects of laparoscopic surgery on the survival of patients.Methods: Twenty-three patients with clinical stage I and IIa endometrial cancer were treated by laparoscopy (laparoscopy group [LS]). The surgical procedures included hysterectomy, salpingo-oophorectomy, and para-aortic-pelvic lymphadenectomy. Peri-operative morbidities and outcomes were compared with 20 control patients who were treated with traditional open surgery (laparotomy group [LT]). The recurrence rate, overall survival, and progression-free survival were also compared between the groups.Results: All 23 patients were treated successfully with laparoscopy. The mean operative time was 419.5 and 321.8 min in the LS and LT groups, respectively. Two intra-operative and 5 post-operative complications occurred in the LS group, but the complication rates were not significantly different from in the complications in the LT group. An earlier recovery and a shorter hospital stay were features of the LS group. There were no differences in recurrence rate, progression-free survival, and overall survival between the LS and LT groups.Conclusion: Laparoscopic surgery of early-stage endometrial cancer is a valid alternative to traditional open surgery, with an earlier recovery and improved quality of life without compromising prognosis.
腹腔镜手术治疗早期子宫内膜癌:在王子总医院的围手术期结果和预后
目的:本研究的目的是报告腹腔镜手术治疗早期子宫内膜癌的可行性,并评估腹腔镜手术对患者生存的影响。方法:对23例临床I期、IIa期子宫内膜癌患者进行腹腔镜治疗(腹腔镜组[LS])。手术包括子宫切除术、输卵管-卵巢切除术和主动脉-盆腔旁淋巴结切除术。将20例采用传统开腹手术治疗的对照组(开腹手术组[LT])围手术期发病率和预后进行比较。比较两组的复发率、总生存期和无进展生存期。结果:23例患者均经腹腔镜手术治疗成功。LS组和LT组平均手术时间分别为419.5 min和321.8 min。LS组术中并发症2例,术后并发症5例,并发症发生率与LT组无明显差异。较早的恢复和较短的住院时间是LS组的特点。LS组和LT组在复发率、无进展生存期和总生存期方面没有差异。结论:腹腔镜手术治疗早期子宫内膜癌是传统开放手术的一种有效的替代方法,恢复较早,生活质量提高,预后良好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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