EP58 Procedural and functional outcomes for aspiration thrombectomy in acute ischemic stroke patients with differing clot dwell times: A subset analysis from the COMPLETE registry

Abstract

subset analysis from a global prospective registry of adults with AIS was performed to evaluate impact of clot dwell time on functional outcomes following AT with the Penumbra System. Inclusion criteria were M1 occlusion, witnessed stroke, baseline mTICI 0 – 2a, and onset to puncture time of 0 – 24 hours.Patients with multiple emboli, proximal stenosis, or tandem lesions were excluded. Results Among 148 patients included (mean age 67.4, 57% female), 67 had clots <=3 hours and 81 had clots >3 hours. Older clots had lower ASPECTS (median 8.0 [IQR 6.0, 9.0] versus 9.0 [8.0, 10.0] p=0.0003) and higher NIHSS (13.0, [9.0, 18.0] versus 16.0 [11.0, 20.0] p=0.0005) at baseline. clots required more passes (2.0 [1.0, 3.0] versus 1.0 [1.0, 2.0], p=0.0066), and time to mTICI 2b-3 reperfusion ( median 27.0 [17.0, 42.0] versus 17.0 [13.0, 29.0] minutes, p=0.0094). Each