A practical reconstruction algorithm for multifocal cone beam SPECT

Z. Cao, B. Tsui
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Abstract

Multifocal cone-beam collimation has been proposed for cardiac SPECT (single photon emission computed tomography) imaging to increase sensitivity over the heart without truncation of activity distribution in the chest. An accurate and efficient algorithm has been derived for multifocal fan-beam SPECT reconstruction and has been extended to multifocal cone-beam SPECT reconstruction. In the multifocal fan-beam algorithm, the projection data were weighted and filtered for every discrete distance from the detector plane, and then the filtered data were interpolated for a given image point in the backprojection. Thus, the backprojection was carried out only once at a projection view. The multifocal cone-beam algorithm was evaluated using the simulated 3-D Defrise slab phantom and the 3-D Shepp-Logan head phantom. In addition, a preliminary study to evaluate the multifocal cone-beam collimator was performed, in which effects of the focal length distribution and the radius-of-rotation (ROR) on the reconstructed image quality were examined. The image quality was improved with decreased ROR.<>
一种实用的多焦锥束SPECT重建算法
多焦点锥束准直已被提议用于心脏SPECT(单光子发射计算机断层扫描)成像,以增加心脏的灵敏度,而不会截断胸部的活动分布。推导了一种精确、高效的多焦点扇形波束SPECT重建算法,并将其推广到多焦点锥形波束SPECT重建中。在多焦点扇形波束算法中,对距离探测器平面每隔一段离散距离的投影数据进行加权滤波,然后对反投影中给定的图像点进行插值处理。因此,在投影视图中只进行一次反向投影。利用模拟的三维Defrise平板幻影和三维Shepp-Logan头部幻影对多焦点锥束算法进行了评估。此外,对多焦锥束准直器进行了初步的评价研究,考察了焦距分布和旋转半径(ROR)对重建像质量的影响。图像质量随着ROR的降低而提高。
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