Experimental study and characterization of Chitosan-HAP composite as orthopedic implant material

Abstract

This study is focused on the preparation of HAp-chitosan composite using solid state mixing by dry ball milling method and detailed characterization of physical, mechanical, micro structural and biological properties. Density and porosity was obtained in the range of 1700-2500 kg/m3 and 3-36% respectively. Hardness was also measured before and after S.B.F exposure of the sample. In vitro bio mineralization test of nano HAp chitosan composite was carried out in S.B.F exposure. The amount of weight increase due to the formation of apatite on the composite surface was measured by analytical balance and morphology change on the surface was observed by scanning electron microscope (SEM). Characterization of produced apatite was achieved by x-ray diffraction.