THE LINK BETWEEN LIPIDIC PROFILE, DEPRESSION AND CARDIOVASCULAR DISEASE

Abstract

The purpose of this study was to identify the connection between cardiovascular disease and depression taking lipid profile as a common risk factor in the occurrence of both pathologies. Materials and methods: 100 patients were examined for 3 months, admitted to the internal medicine department of St. Andrew's Emergency Hospital in Galati. Anamnesis was collected; electrocardiogram, objective examination and lipid profile were performed. The Hamilton scale (HDRS-17) was used to assess depression. Results: In patients with depression, an increased prevalence of dyslipidaemia and obesity was detected, especially in women. Of 10 women with mild and severe depression, all had altered lipid profile, obesity or overweight and increased risk of cardiovascular disease. Conclusions: Although it is claimed that depression would be an individual risk factor for the occurrence of an adverse cardiac event, the comprehensive pathophysiological approach allows the identification of risk factors for both CVD and depression as being largely common. Therefore, a coexistence relationship is created. The other possible situations may arise due to the involvement of individual protective factors and genetic vulnerability. As a result, treatment of depression may reduce risk of cardiovascular event in some cases.