Congenital mesoblastic nephroma in a premature neonate with initial presentation of hematuria – A case report with review of literature

I. Dhal, Goutami Dasnayak, S. Saxena
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Abstract

Congenital mesoblastic nephroma (CMN) is a rare tumor of infancy and consists of 3%–10% of cases among all the pediatric renal tumors. Histologically, it can be classic, cellular, and mixed subtypes, with the cellular variant being difficult to differentiate from Wilms tumors and more aggressive. In this report, macroscopic hematuria was noticed first, and a right renal mass was detected in a 32-week-old premature female neonate, who was born to a 30-year-old woman by emergency cesarean section. Nephrectomy was performed, and histopathological examination of the operated specimen revealed features of cellular variant of CMN.
以血尿为首发表现的早产新生儿先天性间母细胞肾瘤1例并文献复习
先天性间母细胞肾瘤(CMN)是一种罕见的婴儿期肿瘤,约占小儿肾肿瘤的3%-10%。组织学上可分为经典亚型、细胞亚型和混合亚型,细胞亚型难以与Wilms肿瘤区分,且更具侵袭性。在本报告中,一名30岁妇女急诊剖宫产所生的32周早产女性新生儿,首先发现肉眼血尿,并发现右肾肿块。行肾切除术,手术标本的组织病理学检查显示CMN的细胞变异特征。
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