Extracts of Citrus Reticulata (Rutaceae) Fruit Peels Accelerate the onset of Toxicity of Cerastes Cerastes venom in Albino Mice

Abstract

To investigate the effect of aqueous and methanolic extracts of Citrus reticulata (Rutaceae) Fruit Peels on Cerastes cerastes venom. The decline in the mean survival time of the male albino swiss mice were used to deduce the venom property in the presence and absence of aqueous and methanolic extracts of Citrus reticulata (Rutaceae) fruit peels. The aqueous and methanolic extracts of Citrus reticulata (Rutaceae) fruit Peels significantly decrease the mean survival time compared to the venom alone. From these results it was evident that the toxicity of Cerastes cerastes venomis increased significantly in the presence of Citrus reticulata in a dose dependent manner.