Índice de abreviaturas

Abstract

With the introduction of Combined Antiretroviral Therapy, individuals infected by the Human Immunodeficiency Virus have a longer life expectancy and greater susceptibility to non-defining malignancies of Acquired Immunodeficiency Syndrome such as oral squamous cell carcinoma. In these individuals, oral squamous cell carcinoma is more common in men, over 50, smokers and alcoholics, and the vast majority present in an advanced stage with a worse prognosis. Human papillomavirus, immunosuppression and genetic alterations have also been implicated as responsible for oral squamous cell carcinoma in individuals infected by the Human Immunodeficiency Virus. A narrative review of the literature was performed and it was observed that individuals infected by the Human Immunodeficiency Virus who are smokers, alcoholics, carry oncogenic HPV and with a CD4 + T cell count < 200 cells/μL, are at higher risk of developing oral squamous cell carcinoma with worse prognosis than immunocompetent individuals.