Haiping Liu, Wei Lin, Spencer R Leibow, Alexander J Morateck, Malini Ahuja, S. Muallem
{"title":"TRPC3 channel gating by lipids requires localization at the ER/PM junctions defined by STIM1","authors":"Haiping Liu, Wei Lin, Spencer R Leibow, Alexander J Morateck, Malini Ahuja, S. Muallem","doi":"10.1083/jcb.202107120","DOIUrl":null,"url":null,"abstract":"PI(4,5)P2, a key lipid at ER/PM junctions, has multiple roles in regulating TRPC channels, which includes recruitment of the channel to the junctions to facilitate activation by receptor stimulation, channel pore opening, and channel ionic selectivity.","PeriodicalId":343306,"journal":{"name":"The Journal of Cell Biology","volume":"427-429 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Cell Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1083/jcb.202107120","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 11
Abstract
PI(4,5)P2, a key lipid at ER/PM junctions, has multiple roles in regulating TRPC channels, which includes recruitment of the channel to the junctions to facilitate activation by receptor stimulation, channel pore opening, and channel ionic selectivity.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
