Impact of COVID-19 Vaccination on the Trend of Hospital Admission and Mortality in Two Tertiary Care Hospitals in the United Arab Emirates: A Retrospective Study

New Emirates Medical Journal Pub Date : 2023-03-16 DOI:10.2174/04666230316121757

A. A. Zaabi, R. Pradhan, L. Ahmed, N. A. Al Kaabi, Waddah Ibrahim El Subki

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Abstract

To investigate the impact of COVID-19 vaccines in the United Arab Emirates (UAE) on the trend of COVID-19-related hospitalization, intensive care unit (ICU) admissions, and case fatality rate (CFR), this retrospective chart review was conducted. Real-world evidence from the Middle East about the effectiveness of COVID-19 vaccination is still lacking. We included patients admitted to two tertiary hospitals from October 2020 to July 2022. Patients were categorized into non-vaccinated, partially-vaccinated, and fully-vaccinated groups. To investigate the impact of COVID-19 vaccines in the United Arab Emirates (UAE) on the trend of COVID-19-related hospitalization, intensive care unit (ICU) admissions, and case fatality rate (CFR), this retrospective chart review was conducted. A total of 2277 cases were included, with 27.49% being non-vaccinated. The monthly trend of admitted patients dropped from 1264 (56.50%) cases in the first half of 2021 to 194 (8.67%) cases in the first half of 2022, with a reduction rate of 84.65%. The trend of ICU admission followed the overall hospital admission rate, with an overall CFR of 0.88%, 95% CI (0.54% to 1.35%), and a virulence rate of 1.76%, 95% CI (1.26% to 2.38%). The incidence of ICU admission in the unvaccinated group was 4.79%, compared to 0% and 0.97% in the partially-vaccinated and fully-vaccinated groups, respectively (p <0.001). The CFR was significantly (p <0.001) higher in the unvaccinated group 2.88%, 95% CI (1.71 to 4.51) than in the partially-vaccinated 0%, 95% CI (0% to 0.59%) and fully-vaccinated groups 0.19%, 95% CI (0.02% to 0.70%). Among the study population, COVID-19 vaccines showed promising efficacy in reducing the trend of COVID-19-related hospitalization, ICU admission, and mortality. Full vaccination might reduce the burden of COVID-19 on healthcare. A total of 2277 cases were included, with 27.49 None

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COVID-19疫苗接种对阿联酋两家三级医院住院率和死亡率趋势的影响:一项回顾性研究

为了解阿拉伯联合酋长国(UAE) COVID-19疫苗对COVID-19相关住院趋势、重症监护病房(ICU)入院率和病死率(CFR)的影响，本研究进行回顾性图表回顾。来自中东的关于COVID-19疫苗接种有效性的真实证据仍然缺乏。我们纳入了2020年10月至2022年7月在两家三级医院住院的患者。患者分为未接种疫苗组、部分接种疫苗组和完全接种疫苗组。为了解阿拉伯联合酋长国(UAE) COVID-19疫苗对COVID-19相关住院趋势、重症监护病房(ICU)入院率和病死率(CFR)的影响，本研究进行回顾性图表回顾。共纳入2277例，其中27.49%未接种疫苗。月入院人数从2021年上半年的1264例(56.50%)下降到2022年上半年的194例(8.67%)，下降率为84.65%。ICU住院趋势与整体住院率一致，总CFR为0.88%，95% CI(0.54% ~ 1.35%)，毒力率为1.76%，95% CI(1.26% ~ 2.38%)。未接种组ICU住院率为4.79%，部分接种组为0%，完全接种组为0.97%，差异有统计学意义(p <0.001)。未接种疫苗组的CFR (2.88%， 95% CI(1.71 ~ 4.51))显著高于部分接种疫苗组(0% ~ 0.59%)和完全接种疫苗组(0.19%，95% CI(0.02% ~ 0.70%))。在研究人群中，COVID-19疫苗在降低COVID-19相关住院率、ICU住院率和死亡率趋势方面显示出良好的疗效。全面接种疫苗可能会减轻COVID-19对医疗保健的负担。共纳入病例2277例，无病例27.49例

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来源期刊

New Emirates Medical Journal

CiteScore

0.10

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0.00%

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