A microwave sensor dedicated to dielectric spectroscopy of nanoliter volumes of liquids medium and flowing particles

2015 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems (BioWireleSS) Pub Date : 2015-01-25 DOI:10.1109/BIOWIRELESS.2015.7152119

A. Landoulsi, C. Dalmay, A. Bessaudou, P. Blondy, A. Pothier

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引用次数: 2

Abstract

This paper presents a RF biosensor dedicated to the microwave dielectric spectroscopy on nanoliter volumes of liquids or to the detection and analysis on flowing microscale particles. This sensor uses a microfluidic network in order to guide the liquid and drive the particles to analyze. Once properly calibrated this sensor should allow measuring the intrinsic dielectric properties of unknown liquid medium and even individual characteristics of flowing particles. Indeed characterizations done on small volumes of liquids with this device showed a good agreement with macro scale measurements done using a coaxial probe. To demonstrate its sensing capabilities, experiments with polystyrene beads have been first performed and compared with 3D electromagnetic simulations which show that potential high detection sensitivity can be expected. This opens attractive prospects in the frame of microwave dielectric spectroscopy for microanalysis of various dielectric particles like biological cells as example.

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一种微波传感器，专门用于纳升体积的液体介质和流动颗粒的介电光谱

本文介绍了一种射频生物传感器，专门用于纳升体积液体的微波介电光谱或流动微尺度颗粒的检测和分析。该传感器采用微流控网络来引导液体并驱动粒子进行分析。一旦正确校准，这种传感器应该可以测量未知液体介质的固有介电特性，甚至流动颗粒的个别特性。事实上，用这种装置对小体积液体进行的表征与用同轴探头进行的宏观测量结果很好地吻合。为了证明它的传感能力，首先用聚苯乙烯珠进行了实验，并与三维电磁模拟进行了比较，结果表明它具有很高的探测灵敏度。这为以生物细胞为例的各种介电粒子的微分析在微波介电光谱的框架下开辟了诱人的前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

2015 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems (BioWireleSS)

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