Neutrophil-lymphocyte ratio in patients with ankylosing spondylitis

Abstract

Amac: Bu calismanin amaci, ankilozan spondilit (AS) hasta- larindaki inflamasyon ile notrofil-lenfosit orani (NLO) arasindaki iliskiyi belirlemektir. Yontem: Ankilozan spondilit tanili 40 hasta ve 30 saglikli gonullu calismaya dahil edildi. Tum veriler yatan ve polik- linik hasta kayit veritabanindan elde edildi. Tum olgularin Bath Ankilozan Spondilit Hastalik Aktivite Indeksi (BAS- DAI), tam kan sayimi (TKS), CRP ve ESH'i da kapsiyan ayrin- tili fizik muayene ve laboratuvar bulgulari kaydedildi. Lenfosit ve notrofil sayisi otomatik TKS'nin bir parcasi olarak olculdu. Bulgular: Akut- faz reaktani olan CRP ve ESH kontrol gru- buna gore hasta grubunda anlamli olarak daha yuksekti (p 0.05). Sonuc: Bu calismada NLO duzeylerinin AS hastalarinda saglikli bireylere gore anlamli olarak yuksek olmadigi goruldu. Bu sonuc NLO'nun AS hastalarinda sistemik inf- lamasyonu degerlendirmede uygun bir olcu birimi olmadi- gini gotermektedir. Bizim elde ettigimiz bu on sonuclarin daha ileri calismalarla tamamlanmasi gerektigine inaniyo- ruz. Objective: The purpose of the present study is to determine the association between neutrophil-lymphocyte ratio (NLR) and inflammation in ankylosing spondylitis (AS). Method: Forty patients with ankylosing spondylitis and 30 healthy volunteers were included in the study. All data were obtained from patient registry database from in-patient and out-patient clinics. Detailed physical examination, and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) were recorded. Complete blood count (CBC), CRP and ESR were performed recorded as laboratory tests in all participants. Lymphocyte and neutrophil counts were measured as part of the automated CBC. Results: The CRP, which is an acute-phase reactant, and ESR were significantly higher in the patient group than those in the control group (p0.05). Conclusion: We observed that NLR levels weren't significantly higher in AS patients compared to healthy individuals. NLR hasn't seem a reasonable measure to detect systemic inflam- mation in AS patients. We believe that our preliminary results need to be complemented with further studies.