Inhibition of Deamination of Arabinosylcytosine (NSC-63878) by Rhodium(II) Acetate.

Cancer chemotherapy reports Pub Date : 1975-05-01

S H Lee, D L Chao, J L Bear, A P Kimball

引用次数: 0

Abstract

The nobel metal "cage" complex, rhodium(II) acetate, was found to inhibit the deamination of the fraudulent nucleoside, arabinosylcytosine. Potent inhibition of a purified cytidine deaminase from mouse kidney was observed when either cytidine or arabinosylcytosine was used as substrate.

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醋酸铑对阿拉伯糖胞嘧啶(NSC-63878)脱胺反应的抑制作用

诺贝尔金属“笼”络合物，醋酸铑(II)，被发现抑制假核苷，阿拉伯糖胞嘧啶的脱胺作用。当胞苷或阿拉伯糖胞嘧啶作为底物时，观察到从小鼠肾脏纯化的胞苷脱氨酶的有效抑制作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cancer chemotherapy reports

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