Impact of Globally Fair COVID-19 Vaccination: An Analysis based on Agent-Based Simulation

K. Zia, Muhammad Shafi
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Abstract

In this paper, an Agent-Based Model (ABM) is proposed to evaluate the impact of COVID-19 vaccination drive in different settings. The main focus is to evaluate the counter-effectiveness of disparity in vaccination drive among different regions/countries. The proposed model is simple yet novel in the sense that it captures the spatial transmission-induced activity into consideration, through which we are able to relate the transmission model to the mutated variations of the virus. Some important what-if questions are asked in terms of the number of deaths, the time required, and the percentage of population needed to be vaccinated before the pandemic is eradicated. The simulation results have revealed that it is necessary to maintain a global (rather than regional or country-oriented) vaccination provisioning in case of a new pandemic or continual efforts against COVID-19, instead of a self-centered approach.A simplistic agent-based model of virus transmission is used consisting of minimal states of susceptible, vaccinated, infected, and recovered. A moving agent in one of these states is tightly bound to the underlying space, where the space is divided into regions to evaluate the region-based vs. global vaccination drive. Additionally, the virus gets mutated, where the extent of mutation is directly related to spatial activity representing the transmissions. And the inactivity is directly proportional to the mutated variant at a location. The results of the simulation suggest that it is necessary to maintain a global (rather than regional or country-oriented) vaccination drive in case of a new pandemic or continual efforts against COVID-19. It results in a lesser number of deaths, time, and quantity of vaccination required.
全球公平COVID-19疫苗接种的影响:基于agent模拟的分析
本文提出了一种基于agent的模型(ABM)来评估不同环境下COVID-19疫苗接种运动的影响。主要重点是评估不同区域/国家之间疫苗接种活动差异的反效果。所提出的模型简单而新颖,因为它将空间传播诱导的活动考虑在内,通过这种考虑,我们能够将传播模型与病毒的突变变异联系起来。在死亡人数、所需时间和在大流行被根除之前需要接种疫苗的人口百分比方面,提出了一些重要的假设问题。模拟结果表明,如果发生新的大流行或持续进行防疫工作,有必要维持全球(而不是以地区或国家为中心)的疫苗供应,而不是以自我为中心。使用了一种简单的基于药剂的病毒传播模型,包括易感、接种疫苗、感染和恢复的最小状态。处于这些状态之一的移动代理与底层空间紧密绑定,其中空间被划分为区域,以评估基于区域的疫苗接种与全球疫苗接种驱动。此外,病毒会发生变异,变异的程度与代表传播的空间活动直接相关。而不活跃程度与某个位置的变异成正比。模拟结果表明,如果发生新的大流行或持续努力抗击COVID-19,有必要保持全球(而不是以区域或国家为导向)的疫苗接种运动。它减少了死亡人数,减少了所需的疫苗接种时间和数量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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