The Mechanism of the Effect of Exercise Training on the Morphology of Neurons in the Caudate Putamen of the Mice

Z. Wu
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Abstract

The purpose of this article is to study the effect of exercise training on neuronal morphology of somatosensory regions and caudate putamen in the cerebral cortex of mice. In this paper, 20 female mice of Kunming species and 20 mice were paired and randomly assigned to the exercise group and the control group. The exercise group mice performed physical activities. After 8 weeks of exercise training on the exercise treadmill, in a quiet state, tissue sections of the somatosensory area of the cerebral cortex were prepared and HE stained. The changes in tissue morphology were observed under an optical microscope and cell counts were performed. The mice were sacrificed during sexual maturity and senescence, and seven morphological parameters in the frontal cortex neurons of two types of mice were measured by cytomorphometry. The test was used to compare the differences between the parameters of different groups. To a certain extent, it can promote the increase of 12% in the nucleolus of canine pyramidal cells in the sensory area of the cerebral cortex of the white mice, and the increase in the density of the spinal cyst spines in the middle pyramidal cells of the sixth layer and the middle astrocytes of the caudal shell. The conclusion shows that proper exercise can increase the activity of neurons in the caudate putamen of the rat brain, which is beneficial to the transmission of neurons and the release of transmitters, and promotes the function of the brain.
运动训练对小鼠尾状壳核神经元形态影响的机制
本文旨在研究运动训练对小鼠大脑皮层体感觉区和尾状壳核神经元形态的影响。本文选取昆明种雌性小鼠20只和20只小鼠进行配对,随机分为运动组和对照组。运动组小鼠进行体力活动。在安静状态下,在运动跑步机上进行8周的运动训练后,制备大脑皮层体感区组织切片并进行HE染色。在光学显微镜下观察组织形态的变化并进行细胞计数。分别在性成熟和性衰期间处死小鼠,用细胞形态术测定两种小鼠额叶皮层神经元的7个形态学参数。该检验用于比较不同组间参数的差异。在一定程度上可促进小白鼠大脑皮层感觉区犬锥体细胞核仁增加12%,第六层中间锥体细胞和尾壳中间星形胶质细胞棘囊棘密度增加。结论表明,适当的运动可以增加大鼠大脑尾状壳核神经元的活动,有利于神经元的传递和递质的释放,促进大脑功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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