P101 Mortality in patients requiring home mechanical ventilation during the COVID-19 pandemic: experiences of a regional specialist ventilation unit

R. D'Cruz, N. Shah, A. Learoyd, O. J. Elias, M. Mackie, N. Weston, G. Kaltsakas, E. Suh, P. Marino, M. Ramsay, S. Srivastava, H. Pattani, J. Steier, N. Hart, P. Murphy
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Abstract

P101 Figure 1(A) Monthly mortality of patients under Lane Fox Respiratory Service follow-up, dotted lines represent upper and lower bounds of 95% confidence intervals (B) Proportion of home mechanical ventilation (HMV) users in each disease category who died between 1st March and 30th ApriI by year[Figure omitted. See PDF]ConclusionsDeaths amongst HMV users at our regional ventilation centre were highest in the first two months following the onset of the COVID-19 pandemic. A subsequent fall in mortality may relate to effective shielding advice following national lockdown and departmental guidance offered. The majority of deaths were in patients with obesity-related respiratory failure. These data support previous observations that obesity is a major risk factor for adverse outcomes in patients with COVID-19.
P101 COVID-19大流行期间需要家用机械通气的患者死亡率:区域专科通气单位的经验
P101图1(A) Lane Fox呼吸服务随访患者每月死亡率,虚线表示95%置信区间的上界和下界(B)每年3月1日至4月30日期间每个疾病类别中家庭机械通气(HMV)使用者死亡的比例[图略]。结论:在我们的区域通风中心,HMV使用者的死亡率在COVID-19大流行发生后的头两个月最高。随后的死亡率下降可能与国家封锁和部门指导后提供的有效防护建议有关。大多数死亡是与肥胖相关的呼吸衰竭患者。这些数据支持了之前的观察结果,即肥胖是COVID-19患者不良后果的主要危险因素。
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