The Role of Blood Microbiome and Microbial Product Translocation in Disease Pathogenesis

Abstract

Circulation has been considered in a sterile condition in individuals without live microbial infections. However, recent publications from our group and others highlight detection of blood microbiome or microbial molecules in healthy individuals and individuals with various diseases, as well as their potential roles in disease pathogenesis. In this review, we introduce the published studies and research advancement in the field of blood microbial and microbial translocation in disease immunopathogenesis.