PREVENTION OF INFECTIOUS COMPLICATIONS OF TRACHEOSTOMY IN PATIENTS WITH HEAD AND NECK CANCER PATHOLOGY

O. V. Burjan, N. O. Yurevich, Yu. Yu. Kuchmiy, V. O. Zmeyev
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Abstract

Summary. Introduction. A tracheostomy is still widely used in the head and neck oncology practice, but the rate of infectious complications remains high. Goal. Optimization of the prevention and treatment of the tracheostomy complications in patients with oncological pathology of the head and neck based on taking into account the flora that is seeded from the tracheostomy. Materials and methods. The 1st stage of the study consisted in examining of the 100 patients after tracheostomies performed in the period 2018-2022 (planned — 76, emergency — 24). The age of the patients ranged from 40 to 70 years old. The indication for the tracheostomy was obstruction of the respiratory tract by a tumor process of the larynx and the laryngopharynx. All surgery operations were performed under the local infiltration anesthesia, according to the standard technique for the permanent tracheostomy. At the 2nd stage, the proposed methods of the postoperative management of the patients to prevent the infectious complications were evaluated: processing of the cannula with a combination of 0.01 % solution of the miramistin with 10 mg of the chymotrypsin or a combination of 0.5 % solution of the dioxidin and 10 mg of the chymotrypsin. Results and their discussion. At the 1st stage of the study, various complications were detected, but in all cases there were infectious complications. Most often, after 7 days, Pseudomonas aeruginosa was cultured from the trachea, followed by Acinetobacter baumannii in 2nd place. The use of 0.02 % chlorhexidine solution to process the cannula was not effective. The flora that is cultured determines the antiseptic agent that should be used to process the cannula. Conclusions. 1. Infectious complications after the tracheostomy are inevitable due to disruption of the natural path of air movement. 2. The flora sown from the tracheostomy cannula within 14 days after the tracheostomy is diverse. 3. It is advisable to use double-lumen tracheostomy cannulas, the inner part of which should be processing with the antiseptics depending on the flora found in the tracheal contents. 4. The combination of the 0.01 % miramistin solution with 10 mg chymotrypsin for the cannula processing is effective against P. aeruginosa. A combination of 0.5 % dioxidin solution and 10 mg chymotrypsin is effective against S. aureus, A. baumanii and K. pneumoniae.
头颈部肿瘤病理患者气管切开术感染并发症的预防
总结。介绍。气管切开术仍然广泛应用于头颈部肿瘤的实践,但感染性并发症的发生率仍然很高。的目标。头颈部肿瘤病理患者气管切开术并发症的预防和治疗的优化,基于气管切开术所播种的菌群。材料和方法。研究的第一阶段包括检查2018-2022年期间气管切开术后的100例患者(计划76例,急诊24例)。患者年龄在40 ~ 70岁之间。气管切开术的指征是喉部和喉咽部肿瘤进程引起的呼吸道阻塞。所有手术均在局部浸润麻醉下,按照永久性气管切开术的标准技术进行。在第二阶段,评估了建议的预防感染并发症的患者术后管理方法:用0.01%的米米司汀溶液和10mg的凝乳胰蛋白酶联合处理插管,或0.5%的二氧化英溶液和10mg的凝乳胰蛋白酶联合处理。结果和讨论。在研究的第一阶段,发现了各种并发症,但所有病例都有感染性并发症。最常见的是,7天后从气管中培养铜绿假单胞菌,其次是鲍曼不动杆菌。使用0.02%氯己定溶液加工套管效果不佳。培养的菌群决定了应用于处理套管的防腐剂。结论:1。气管切开术后的感染并发症是不可避免的,因为空气运动的自然路径被破坏。2。气管切开术后14天内从气管切开术套管中播种的菌群是多种多样的。3所示。建议使用双腔气管切开术套管,其内部应根据气管内容物中发现的菌群用防腐剂处理。4所示。0.01% miramistin溶液与10 mg胰凝乳蛋白酶联合用于插管处理对铜绿假单胞菌有效。0.5%二氧化英溶液和10毫克胰凝乳蛋白酶的组合对金黄色葡萄球菌、鲍曼不动杆菌和肺炎克雷伯菌有效。
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