Environmental Factors and Multiple Myeloma Risk: A Population-Based Retrospective Cohort Study in the United States

Abstract

Multiple myeloma (MM) is claimed to be a leading fatal cancer in the United States. A population-based retrospective cohort study was conducted to examine the relationship between the risk of multiple myeloma and environmental factors including CO2 intensity leaked by oil equivalent energy use, PM2.5, total greenhouse gas emission, and sanitized water usage, respectively, and to further determine any association's worldwide universality. We used multivariate unconditional analysis (ANOVA) to examine the distributions of MM incidence rate among groups with selected characteristics. In addition, we used multivariate conditioned generalized linear regression models to estimate effects of each environmental factor on MM incidence rate. A rate. Among black racial groups aged from 65 to 74 years in the United States, total greenhouse gas emission had a positive effect on the cancer risk as predicted. However, in accordance with empirical work to date, our comparative analyses revealed that MM incidence rate was not significantly associated with an increase in other in other variates relative to age. Thus, our combined results require further confirmation in other populations with specific personal information.