Trigeminal schwannoma exhibiting orofacial pain

Frankantony P Britto, Sansriti Narain, JVarsha R. Shetty, HP Narasimha Murthy, Sandeep Singh
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Abstract

Schwannomas are benign nerve sheath tumors arising from the Schwann cells. Trigeminal schwannomas account for 1%–8% of all intracranial schwannomas and 0.1%–0.5% of intracranial tumors. Intracranial trigeminal schwannomas are usually diagnosed in the third and fourth decades of life but can present at any age. The symptoms usually present with trigeminal hyperesthesia, facial pain & headache. Detailed medical history needs to be taken in these patients as there is a possibility of trigeminal schwannoma symptoms presenting as pain of odontogenic origin. The following case report provides a case of trigeminal schwannoma presenting as pain of odontogenic origin. A 37-year-old male complained of pain in the upper right quadrant for 1 week. The pain was mild to moderate in intensity and would increase while clenching his teeth. The pain would not relieve on taking over-the-counter analgesics and would aggravate due to anxiety, lack of sleep, or after consuming drinks with caffeine and also foods having a sour taste. Brushing on the upper right quadrant would also cause a tingling sensation on the right side of the face. Intraoral examination and diagnosis involving 12, 13, 14, and 15 did not reveal any odontogenic cause. Medical history revealed a diagnosis of trigeminal schwannoma of the right side a year back. The trigeminal schwannoma was treated with stereotactic radiation 03 months back. Due to this positive finding in the medical history and probable cause for the intraoral pain, the patient was referred back to his neurosurgeon, who prescribed a 7-day course of methylprednisolone; the steroid regimen resulted in complete cessation of his pain.
三叉神经鞘瘤表现为口面部疼痛
神经鞘瘤是源于雪旺细胞的良性神经鞘肿瘤。三叉神经鞘瘤占颅内神经鞘瘤的1%-8%,占颅内肿瘤的0.1%-0.5%。颅内三叉神经鞘瘤通常在生命的第三和第四十年被诊断出来,但可以出现在任何年龄。症状通常表现为三叉神经感觉亢进、面部疼痛和头痛。这些患者需要详细的病史,因为有可能出现三叉神经鞘瘤症状,表现为牙源性疼痛。下面的病例报告提供了一个病例三叉神经鞘瘤表现为牙源性疼痛。37岁男性主诉右上腹疼痛1周。疼痛的强度在轻度到中度之间,当他咬紧牙关时疼痛会加剧。服用非处方镇痛剂不会减轻疼痛,而且会因焦虑、睡眠不足或饮用含咖啡因的饮料和吃有酸味的食物而加剧。刷右上象限也会引起右脸的刺痛感。涉及12、13、14和15的口内检查和诊断未发现任何牙源性原因。病史显示一年前诊断为右侧三叉神经鞘瘤。三叉神经鞘瘤于03个月前行立体定向放射治疗。由于这一病史的阳性发现和口腔内疼痛的可能原因,患者被转介给他的神经外科医生,他开了7天的甲基强的松龙疗程;类固醇疗法使他的疼痛完全停止。
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