Optimum dose of aspirin for patients with heart disease

Abstract

A 10-year study on a human subject showed that the optimum dose of aspirin to treat coronary heart disease was about 49 mg daily. If the dose was increased to 56 mg, insignificant and reversible hematuria would occur. If the dose was decreased to 40.5 mg, inadequate efficacy would result. No kidney problem was observed as long as the dose did not exceed 56 mg. These findings are a good supplement to the FDA’s recent new guidance on how to use this medication safely to prevent stroke and heart attack.