In-hospital and Long-term Outcomes of Aortic Arch Surgery

A. Domenech, R. Marenchino, R. Posatini, R. Battellini, J. C. Vázquez, E. Rossi, V. Kotowicz
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Abstract

Background: Treatment of patients with acute or chronic aortic arch disease has been historically associated with poor outcomes. Objective: The aim of this study was to analyze in-hospital and long-term outcomes of aortic arch replacement comparing emergency and elective procedures. Methods: We conducted a retrospective cohort study in patients undergoing aortic arch surgery in a high complexity center between January 2010 and December 2016, with one-year follow-up. Results: A total of 65 patients were included; 65% were men and median age was 71 years. Among postoperative complications, prolonged mechanical ventilation was more common in the emergency than in the elective surgery group (52% vs. 19%, p=0.006). The incidence of reoperation due to bleeding, mediastinitis, stroke, and renal failure requiring dialysis in the postoperative period was not significantly different between both groups. In-hospital mortality was 15% and observed mortality 24%, without significant differences according to emergency or elective procedure. Conclusions: In this cohort of patients undergoing aortic arch surgery, in-hospital mortality and 1-year mortality was similar in patients undergoing emergency or elective surgeries. The risk of mortality during the first year was 4 times greater in patients >75 years than in younger ones. The incidence of mortality and postoperative stroke was similar to that reported by recent registries. The incidence of reoperations due to bleeding was remarkably low. The rate of complications (reoperations due to bleeding, stroke, acute renal failure or infection) was not statistically different between both groups, probably because of lack of power of the sample
主动脉弓手术的住院和远期疗效
背景:急性或慢性主动脉弓疾病患者的治疗历来与不良预后相关。目的:本研究的目的是比较急诊和选择性主动脉弓置换术的住院和长期预后。方法:对2010年1月至2016年12月在某高复杂性中心接受主动脉弓手术的患者进行回顾性队列研究,随访1年。结果:共纳入65例患者;65%为男性,中位年龄为71岁。在术后并发症中,急诊延长机械通气比择期手术组更常见(52% vs. 19%, p=0.006)。两组术后因出血、纵隔炎、脑卒中、肾功能衰竭需要透析的再手术发生率无显著差异。住院死亡率为15%,观察死亡率为24%,根据急诊或择期手术无显著差异。结论:在接受主动脉弓手术的患者队列中,急诊或择期手术患者的住院死亡率和1年死亡率相似。75岁以上患者第一年的死亡风险是年轻患者的4倍。死亡率和术后卒中的发生率与最近的登记报告相似。出血再手术的发生率非常低。并发症(因出血、中风、急性肾功能衰竭或感染而再次手术)的发生率在两组之间没有统计学差异,可能是因为样本的有效性不足
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